Article
Molecular analysis of the six most recurrent mutations in the BRCA1 gene in 87 Spanish breast/ovarian cancer families.
Cancer letters - 30 Jan 1998
Osorio A, Robledo M, Albertos J, Díez O, Alonso C, Baiget M, Benítez J
Abstract excerpt
BRCA1 accounts for nearly all families with multiple cases of both early onset breast and ovarian cancer and about 45% of families with breast cancer only. Although to date more than 200 distinct mutations have been described, several have been found to be recurrent in the gene. We have analyzed...
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