Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of the factor V Leiden mutation using the READIT Assay.

Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology - 1 Mar 2001

Rhodes R B, Lewis K, Shultz J, Huber S, Voelkerding K V, Leonard D G, Tsongalis G J, Kephart D D

Abstract excerpt

BACKGROUND: A variety of methods exist for the detection of single-nucleotide polymorphisms (SNPs) present in amplified segments of genomic DNA. We show the application of a novel SNP scoring tool for analysis of the factor V Leiden mutation. METHODS AND RESULTS: We have developed a novel method for analyzing SNPs. The luciferase-based technique, known as the READIT Technology (Promega Corp, Madison, WI), was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Factor V

Share to Point Mutation

Share to Polymerase Chain Reaction

Share to Polymorphism, Single Nucleotide

Share to Reproducibility of Results

Share to Thrombophilia

Source

Identifiers

PMID: 11257212
DOI: 10.1054/modi.2001.22327

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of the factor V Leiden mutation using the READIT Assay.PMID 11257212Read ↗

READIT: a novel technology used in the interrogation of nucleic acid sequences for single-nucleotide polymorphisms.Semantic proximity Read ↗

Genotyping of factor V G1691A (Leiden) without the use of PCR by invasive cleavage of oligonucleotide probes.Semantic proximity Read ↗

Evaluation of temperature gradient capillary electrophoresis for detection of the Factor V Leiden mutation: coincident identification of a novel polymorphism in Factor V.Semantic proximity Read ↗

Testing for Factor V Leiden (FVL) and Prothrombin G20210A Genetic Variants.Semantic proximity Read ↗

Determination of the factor V Leiden single-nucleotide polymorphism in a commercial clinical laboratory by use of NanoChip microelectronic array technology.Semantic proximity Read ↗

Detection of the factor V Leiden mutation by a modified photo-cross-linking oligonucleotide hybridization assay.Semantic proximity Read ↗

Evaluation of the GeneXpert assay in the detection of Factor V Leiden and prothrombin 20210 in stored, previously classified samples.Semantic proximity Read ↗

A microplate allele-specific oligonucleotide hybridization assay for detection of factor V Leiden.Semantic proximity Read ↗

Analytical evaluation of primer engineered multiplex polymerase chain reaction-restriction fragment length polymorphism for detection of factor V Leiden and prothrombin G20210A.Semantic proximity Read ↗

A multi-site study for detection of the factor V (Leiden) mutation from genomic DNA using a homogeneous invader microtiter plate fluorescence resonance energy transfer (FRET) assay.Semantic proximity Read ↗

A method for homogeneous color-compensated genotyping of factor V (G1691A) and methylenetetrahydrofolate reductase (C677T) mutations using real-time multiplex fluorescence PCR.Semantic proximity Read ↗

Simultaneous allele-specific amplification: a strategy using modified primer-template mismatches for SNP detection--application to prothrombin 20210A (factor II) and factor V Leiden (1691A) gene mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.