Article
[Potential relationship between mutation process induced by low doses of ionizing radiation, and positional dynamics of chromosomes in nuclei of eukaryotic cells].
Radiatsionnaia biologiia, radioecologiia - 1 Jan 2000
Spitkovskiĭ D M, Kuz'mina I V, Veĭko N N, Ermakov A V, Ingel' F I, Makarenkov A A, Pospekhova N I, Salimov A G, Talyzina T A, Karpukhin A V
Abstract excerpt
The mutation process has many stages. The information presented in this article suggest that a cell exposed to low LET radiation in the low-dose range (up to 1 cGy) must almost completely repair all spontaneous and radiation-induced DNA lesions. But reparation of DNA double-stranded breaks (DSB), which are the basis of genome instability has peculiarity. We have shown that the mechanisms of action of low doses...
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