Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic nature of radiation carcinogenesis at low doses.

Chinese medical journal - 1 Jun 1994

Sugahara T, Watanabe M

Abstract excerpt

The present paradigm of radiation-induced carcinogenesis has been based on somatic mutation theory initiating a mutation in somatic cells derived from DNA damage by ionizing radiation. A non-threshold linear model has been assumed from high doses to low doses. As an alternative to this, we are proposing a new model that epigenetic changes induced by low dose irradiation may be a first step of carcinogenesis. Our...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Transformation, Neoplastic
Share to Cricetinae
Share to Cytokines

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Damage

Share to Dose-Response Relationship, Radiation

Share to Embryo, Mammalian

Share to Mesocricetus

Share to Mutation

Source

Identifiers

PMID: 7956477

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic nature of radiation carcinogenesis at low doses.PMID 7956477Read ↗

Ionizing Radiation-Induced Epigenetic Modifications and Their Relevance to Radiation ProtectionSemantic proximity Read ↗

Ionizing Radiation and Human Health: Reviewing Models of Exposure and Mechanisms of Cellular Damage. An Epigenetic PerspectiveSemantic proximity Read ↗

Molecular mechanisms of radiation carcinogenesis and the linear, non-threshold dose response model of radiation risk estimation.Semantic proximity Read ↗

Paradigm Shifts in Radiation Biology: Their Impact on Intervention for Radiation-Induced DiseaseSemantic proximity Read ↗

Health Risks of Low Dose Ionizing Radiation in Humans: A ReviewSemantic proximity Read ↗

Epigenetic DNA Methylation Under the Influence of Low-Dose Ionizing Radiation, and Supplementation with Vitamin B12 and Folic Acid: Harmful or Beneficial for Professionals?Semantic proximity Read ↗

Radiobiological Basis of Low-Dose Irradiation in Prevention and Therapy of CancerSemantic proximity Read ↗

Evidence for beneficial low level radiation effects and radiation hormesisSemantic proximity Read ↗

Progress in low dose health risk research: Novel effects and new concepts in low dose radiobiology.Semantic proximity Read ↗

Carcinogenic effects of low-level ionizing radiation: problems and prospects.Semantic proximity Read ↗

The Dose Window for Radiation-Induced Protective Adaptive ResponsesSemantic proximity Read ↗

Is Ionizing Radiation Harmful at any Exposure? An Echo That Continues to VibrateSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.