Article
Analysis of cancer/testis antigens in sporadic medullary thyroid carcinoma: expression and humoral response to NY-ESO-1.
The Journal of clinical endocrinology and metabolism - 1 Feb 2003
Maio Michele, Coral Sandra, Sigalotti Luca, Elisei Rossella, Romei Cristina, Rossi Guido, Cortini Enzo, Colizzi Francesca, Fenzi Gianfranco, Altomonte Maresa, Pinchera Aldo, Vitale Mario
Abstract excerpt
Cancer/testis antigens (CTA) are tumor-associated antigens expressed during ontogenesis, in a number of solid tumors but not in normal tissues except testis. Most of these CTA are highly immunogenic, eliciting a humoral and cellular response in the patients with advanced cancer, and are useful for tumor-specific immunotherapy. Medullary thyroid carcinoma (MTC) is a neoplasm derived from the parafollicular cells...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
