Article
Plasma tumor necrosis factor alpha levels and the -238*A promoter polymorphism in patients with antiphospholipid syndrome.
Thrombosis and haemostasis - 1 Feb 2001
Bertolaccini M L, Atsumi T, Lanchbury J S, Caliz A R, Katsumata K, Vaughan R W, Kondeatis E, Khamashta M A, Koike T, Hughes G R
Abstract excerpt
OBJECTIVES: To explore the possible involvement of the proinflammatory and prothrombotic cytokine TNFalpha in APS by determining the plasma levels in patients and to test for association of TNFA promoter polymorphisms and HLA class II genotypes with both plasma TNFalpha and disease. PATIENTS AND METHOD: We studied 83 Caucasoid patients with APS and two groups of healthy controls. TNFalpha levels were determined...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.