Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumour necrosis factor-alpha gene promoter region -308 and -376 G-->A polymorphisms in Behçet's disease.

Clinical and experimental rheumatology - 1 Jan 2000

Duymaz-Tozkir J, Gül A, Uyar F A, Ozbek U, Saruhan-Direskeneli G

Abstract excerpt

OBJECTIVE: Contribution of HLA-B51 to the genetic susceptibility for Behçet's disease is well documented and recent studies suggest involvement of other genes. Tumour necrosis factor (TNF) genes are located in the vicinity of the HLA-B locus. Polymorphisms in the promoter region of TNF-alpha gene has been found to be associated with altered TNF secretion, and it may have a prominent role in the increased...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Behcet Syndrome
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HLA-B Antigens

Share to HLA-B51 Antigen

Share to Probability

Share to Promoter Regions, Genetic

Share to Reference Values

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 14727453

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumour necrosis factor-alpha gene promoter region -308 and -376 G-->A polymorphisms in Behçet's disease.PMID 14727453Read ↗

Lack of association of tumor necrosis factor-alpha gene polymorphisms with disease susceptibility and severity in Behçet's disease.Semantic proximity Read ↗

TNF polymorphisms in patients with Behçet disease: a meta-analysis.Semantic proximity Read ↗

Correlation of Tumor Necrosis Factor-α -308G>A Polymorphism with Susceptibility, Clinical Manifestations, and Severity in Behçet Syndrome: Evidences from an Italian Genetic Case-Control Study.Semantic proximity Read ↗

Polymorphisms of Promoter Region of TNF-α Gene in Iranian Azeri Turkish Patients with Behçet's Disease.Semantic proximity Read ↗

The novel -G646A polymorphism of the TNFalpha promoter is associated with the HLA-B51 allele in Korean patients with Behçet's disease.Semantic proximity Read ↗

Tumor necrosis factor gene polymorphisms in Tunisian patients with Behcet's disease.Semantic proximity Read ↗

Mapping the HLA association in Behçet's disease: a role for tumor necrosis factor polymorphisms?Semantic proximity Read ↗

Correlation of tumor necrosis factor-α -308G>A polymorphism with susceptibility, clinical manifestations and severity in Behçet syndrome: evidences from an Italian genetic case-control studySemantic proximity Read ↗

Polymorphisms in the tumor necrosis factor gene and susceptibility to Behcet's disease: an updated meta-analysis.Semantic proximity Read ↗

SNPs in the TNF-α gene promoter associated with Behcet's disease in Moroccan patients.Semantic proximity Read ↗

Association of TNFA promoter region haplotype in Behçet's Disease.Semantic proximity Read ↗

Proinflammatory cytokine gene polymorphisms in Behçet's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.