Article
The functional similarity and structural diversity of human and cartilaginous fish hemoglobins.
Journal of molecular biology - 16 Mar 2001
Naoi Y, Chong K T, Yoshimatsu K, Miyazaki G, Tame J R, Park S Y, Adachi S, Morimoto H
Abstract excerpt
Although many descriptions of adaptive molecular evolution of vertebrate hemoglobins (Hb) can be found in physiological text books, they are based mainly on changes of the primary structure and place more emphasis on conservation than alterations at the functional site. Sequence analysis alone, however, does not reveal much about the evolution of new functions in proteins. It was found recently that there are...
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