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Article

Signal transduction through the ras/Erk pathway is essential for the mycoestrogen zearalenone-induced cell-cycle progression in MCF-7 cells

1 Jan 2001

Abstract excerpt

Zearalenone is a naturally occurring estrogenic contaminant of moldy feeds and is present in high concentrations in dairy products and cereals. Zearalenone was postulated to contribute to the overall estrogen load of women, but the mechanisms of its action are not known. We demonstrated that zearalenone could stimulate the growth of estrogen receptor-positive human breast carcinoma cell line MCF-7. In addition,...

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Share to Genomics, phytochemicals, and oxidative stress
Share to Mycotoxins in Agriculture and Food
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PMID: 11241756
DOI: 10.1002/1098-2744(200102)30:2<88::aid-mc1017>3.0.co;2-e

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