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Article

Involvement of cyclin D1 and E2f1 in zearalenone-induced DNA damage in testis of rats.

Toxicon : official journal of the International Society on Toxinology - 1 Nov 2015

Cheraghi Shabnam, Razi Mazdak, Malekinejad Hassan

Abstract excerpt

This study was designed to evaluate the effect of zearalenone (ZEA) on cell cycle checkpoints cyclin D1 and E2f1 expression at mRNA level and to analyze the estrogen like impact of ZEA on male reproductive system. Thirty mature male rats were randomly assigned into five groups as; control (received 0.5 mL saline normal, i.p.), ZEA-received groups (1, 2 and 4 mg/kg, b.w., i.p.) and 17 β-estradiol-received group...

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Identifiers

PMID: 26408962
DOI: 10.1016/j.toxicon.2015.09.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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