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Article

Autocrine/Paracrine Mechanisms in Human Hematopoiesis

1 Mar 2001

Abstract excerpt

Autocrine/paracrine regulatory mechanisms are believed to play a role in the pathophysiology of several hematologic malignancies. Evidence is accumulating that various growth factors, cytokines, and chemokines are expressed and secreted by normal early and differentiated hematopoietic cells and thus could also regulate normal hematopoiesis in an autocrine/paracrine manner. In this review we summarize recent...

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PMID: 11239164
DOI: 10.1634/stemcells.19-2-99

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