Article
Leukemic stromal hematopoietic microenvironment negatively regulates the normal hematopoiesis in mouse model of leukemia.
Chinese journal of cancer - 1 Dec 2010
Basak Pratima, Chatterjee Sumanta, Das Prosun, Das Madhurima, Pereira Jacintha Archana, Dutta Ranjan Kumar, Chaklader Malay, Chaudhuri Samaresh, Law Sujata
Abstract excerpt
BACKGROUND AND OBJECTIVE: Leukemic microenvironment has a major role in the progression of leukemia. Leukemic cells can induce reversible changes in microenvironmental components, especially the stromal function which results in improved growth conditions for maintaining the malignant leukemic ce...
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