Article
The control of hematopoiesis and leukemia: from basic biology to the clinic.
Proceedings of the National Academy of Sciences of the United States of America - 14 May 1996
Sachs L
Abstract excerpt
Hematopoiesis gives rise to blood cells of different lineages throughout normal life. Abnormalities in this developmental program lead to blood cell diseases including leukemia. The establishment of a cell culture system for the clonal development of hematopoietic cells made it possible to discover proteins that regulate cell viability, multiplication and differentiation of different hematopoietic cell lineages,...
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