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Article

Association between Estrogen Receptor-β Gene Polymorphisms and Ovulatory Dysfunctions in Patients with Menstrual Disorders

1 Jan 2001

Abstract excerpt

Estrogen plays a significant role in human ovulation. It acts as an important positive regulator of the preovulatory gonadotropin surge necessary to initiate the cascade of events leading to ovulation. The steroid hormone exerts its physiological responses through the estrogen receptor (ER), of which two subtypes, ERalpha and ERbeta, are known. ERbeta messenger ribonucleic acid occurs maximally in the ovaries and...

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PMID: 11231990
DOI: 10.1210/jcem.86.1.7098

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