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Article

Antiretroviral resistance in clinical practice.

International journal of STD & AIDS - 1 Mar 2001

Geretti A M, Easterbrook P

Abstract excerpt

Despite the success of potent combination therapy against HIV, a large proportion of patients experiences treatment failure. Due to the high degree of plasticity of the HIV genome, ongoing virus replication in the presence of drug pressure will result in the selection of virus mutants with reduced drug susceptibility. As a result, antiretroviral drug-resistance is a common denominator in treatment failure. Two...

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Identifiers

PMID: 11231866
DOI: 10.1258/0956462011916938

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Source receipt: pubmed, retrieved 7 Sept 2026.

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