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Molecular Genetic Analysis of Two Human Sperm Fibrous Sheath Proteins, AKAP4 and AKAP3, in Men With Dysplasia of the Fibrous Sheath

4 Mar 2001

Abstract excerpt

Dysplasia of the fibrous sheath (DFS) is characterized by male infertility, asthenozoospermia, and morphologically abnormal flagella that possess a severely malformed fibrous sheath. In many cases, DFS is familial, suggesting a genetic component. Human AKAP4 and AKAP3 are structural proteins of the fibrous sheath that also function to anchor protein kinase A to this structure via the regulatory subunit of the...

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PMID: 11229805
DOI: 10.1002/j.1939-4640.2001.tb02184.x

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Molecular Genetic Analysis of Two Human Sperm Fibrous Sheath Proteins, AKAP4 and AKAP3, in Men With Dysplasia of the Fibrous SheathPMID 11229805Read ↗

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