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Article

Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Mar 2001

Trejo J L, Carro E, Torres-Aleman I

Abstract excerpt

Although the physiological significance of continued formation of new neurons in the adult mammalian brain is still uncertain, therapeutic strategies aimed to potentiate this process show great promise. Several external factors, including physical exercise, increase the number of new neurons in the adult hippocampus, but underlying mechanisms are not yet known. We recently found that exercise stimulates uptake of...

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PMID: 11222653
PMCID: PMC6762955

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