Article
Two polymorphisms within interleukin-3 (hIL3) gene detected by mismatch PCR/RFLP.
Genes and immunity - 1 Nov 1999
Nakashima H, Otsuka T, Ohba Y, Akahoshi M, Nagano S, Ogami E, Arinobu Y, Miyake K, Inoue Y, Niiro H, Kaji Y, Niho Y
Abstract excerpt
Two alleles of IL-3 have been reported to GenBank (GenBank M14743, M20137). The sequence difference between these two alleles is at the first nucleotide of the 27th codon (the 131st nucleotide from the initiation site): thymine and cytosine, and leading the amino acid difference: proline and serine (Pro27Ser). The other allelism, thymine and cytosine, was also observed at position -16 of the IL-3 upstream...
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