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Article

Probing structural and functional domains of human P450c17.

Endocrine research - 1 Nov 2000

Auchus R J, Worthy K, Geller D H, Miller W L

Abstract excerpt

Human P450c17 performs at least six chemical transformations, but this spectrum of activity is differentially regulated by structural changes and by redox partner proteins. Furthermore, P450c17 isoforms from different species with approximately 90% amino acid identity exhibit markedly different relative rates for these transformations. Although this phenomenology has been recognized for nearly 20 years, the...

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Identifiers

PMID: 11196445
DOI: 10.3109/07435800009048589

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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