Article
Screening for a D9N common mutation in exon 2 of the LPL gene in Thai normolipidemic and hyperlipidemic subjects.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet - 1 Nov 2000
Tirawanchai N, Yamwong P, Pongrapeeporn K U, Likidlilid A, Ong-Ajyooth S, Amornrattana A
Abstract excerpt
Lipoprotein lipase (LPL) is a multifunctional protein, playing a major role in the hydrolysis of triglyceride-rich lipoproteins. It also affects the maturation of high density lipoprotein (HDL) and low density lipoprotein (LDL). A D9N substitution is a frequent mutation found in exon 2 of the LPL gene. It is due to a G --> A transition causing a substitution of Asp by Asn at amino acid residue 9 of the protein....
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