Article
Genetic screening of the LPL gene in hypertriglyceridaemic patients.
Atherosclerosis - 1 Jul 2008
Wright William T, Young Ian S, Nicholls D Paul, Graham Colin A
Abstract excerpt
Serum triglyceride (TG) level is an important independent risk factor for coronary heart disease, with the lipoprotein lipase (LPL) enzyme playing the major role in regulating the catabolism of TG rich lipoproteins. The complete sequence analysis of the LPL gene was carried out on 19 individuals with extreme hypertriglyceridaemia (HTG; TG>14 mmol/l) with a total of 42 sequence variants being identified, a number...
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