Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dysadherin Overexpression in Pancreatic Ductal Adenocarcinoma Reflects Tumor Aggressiveness: Relationship to E-Cadherin Expression

13 Feb 2003

Abstract excerpt

PURPOSE: The E-cadherin-mediated cell adhesion system is frequently inactivated by multiple mechanisms and is involved in tumor progression in many types of cancer. Recently, we reported the cloning and characterization of dysadherin and showed that it downregulated E-cadherin and promoted metastasis. The aim of this study was to investigate the clinical significance of dysadherin expression and the relationship...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cell death mechanisms and regulation
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12586803
DOI: 10.1200/jco.2003.06.179

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dysadherin Overexpression in Pancreatic Ductal Adenocarcinoma Reflects Tumor Aggressiveness: Relationship to E-Cadherin ExpressionPMID 12586803Read ↗

Duodenal invasion by pancreatic adenocarcinoma: MDCT diagnosis of an aggressive imaging phenotype and its clinical implications.Semantic proximity Read ↗

Large duct type invasive adenocarcinoma of the pancreas with microcystic and papillary patterns: a potential microscopic mimic of non-invasive ductal neoplasia.Semantic proximity Read ↗

Absence of E-Cadherin Expression Distinguishes Noncohesive from Cohesive Pancreatic CancerSemantic proximity Read ↗

N-cadherin and keratinocyte growth factor receptor mediate the functional interplay between Ki-RASG12V and p53V143A in promoting pancreatic cell migration, invasion, and tissue architecture disruption.Semantic proximity Read ↗

The integrin-extracellular matrix axis in pancreatic cancer.Semantic proximity Read ↗

Loss of the CBX7 protein expression correlates with a more aggressive phenotype in pancreatic cancer.Semantic proximity Read ↗

Identification of novel highly expressed genes in pancreatic ductal adenocarcinomas through a bioinformatics analysis of expressed sequence tagsSemantic proximity Read ↗

CD133 facilitates epithelial-mesenchymal transition through interaction with the ERK pathway in pancreatic cancer metastasisSemantic proximity Read ↗

Phenotypical characteristics of undifferentiated carcinoma of the pancreas: a comparison with pancreatic ductal adenocarcinoma and relevance of E-cadherin, alpha catenin and beta catenin expression.Semantic proximity Read ↗

Engrailed‐1 Promotes Pancreatic Cancer MetastasisSemantic proximity Read ↗

N-cadherin expression in breast cancer: correlation with an aggressive histologic variant--invasive micropapillary carcinoma.Semantic proximity Read ↗

Pancreatic carcinoma: correlation between E-cadherin and alpha-catenin expression status and liver metastasis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.