Article
Microsatellite mapping of a susceptible locus within the HLA region for Behçet's disease using Jordanian patients.
Human immunology - 1 Feb 2001
Mizuki N, Yabuki K, Ota M, Verity D, Katsuyama Y, Ando H, Onari K, Goto K, Imagawa Y, Mandanat W, Fayyad F, Stanford M, Ohno S, Inoko H
Abstract excerpt
Behçet's disease (BD) has been established to be associated with HLA-B51. However, it has not been revealed whether the HLA-B51 gene itself or another gene located near the HLA-B gene is directly involved in the pathogenesis of BD. Previously, using Japanese BD patients, our group has narrowed down a BD-causative gene to 46 kb between the MICA and HLA-B genes by means of fine mapping analysis with eight...
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