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Article

Effectiveness of breast cancer surveillance in BRCA1/2 gene mutation carriers and women with high familial risk.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 15 Feb 2001

Brekelmans C T, Seynaeve C, Bartels C C, Tilanus-Linthorst M M, Meijers-Heijboer E J, Crepin C M, van Geel A A, Menke M, Verhoog L C, van den Ouweland A, Obdeijn I M, Klijn J G

Abstract excerpt

PURPOSE: Women with a high breast cancer risk due to a familial predisposition may choose between preventive surgery and regular surveillance. The effectiveness of surveillance in high-risk women and especially BRCA1/2 mutation carriers is unknown. We present first results from a single large family cancer clinic. PATIENTS AND METHODS: Women with breast cancer risk over 15% were examined by physical examination...

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Source

Identifiers

PMID: 11181654
DOI: 10.1200/JCO.2001.19.4.924

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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