Article
Soluble CD95 concentrations are increased in patients with severe systemic lupus erythematosus, but not in their first degree relatives.
Annals of the rheumatic diseases - 1 Mar 2001
van der Linden M W, van Lopik T, Aarden L A, Westendorp R G, Huizinga T W
Abstract excerpt
OBJECTIVE: Plasma concentrations of soluble CD95 (sCD95) are raised in patients with systemic lupus erythematosus (SLE) before clinical relapses become manifest. Increased sCD95 concentrations may therefore be a familial characteristic that is associated with susceptibility to severe disease. To test this, sCD95 concentrations were measured in healthy first degree relatives of patients with severe and non-severe...
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