Article
hprt mutant frequencies, nonpulmonary malignancies, and domestic radon exposure: "postmortem" analysis of an interesting hypothesis.
Environmental and molecular mutagenesis - 1 Jan 2001
Ruttenber A J, Harrison L T, Baron A, McClure D, Glanz J, Quillin R, O'Neill J P, Sullivan L, Campbell J, Nicklas J A
Abstract excerpt
The hypothesis that exposure to domestic radon raises the risk for leukemia and other nonpulmonary cancers has been proposed and tested in a number of epidemiologic studies over the past decade. During this period, interest in this hypothesis was heightened by evidence of increased frequencies of mutations at the hypoxanthine guanine phosphoribosyl transferase (hprt) gene in persons exposed to domestic radon...
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