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Article

Are aberrant BCR--ABL transcripts more common than previously thought?

British journal of haematology - 1 Dec 2000

Wilson G A, Vandenberghe E A, Pollitt R C, Rees D C, Goodeve A C, Peake I R, Reilly J T

Abstract excerpt

We report the use of multiplex polymerase chain reaction (PCR), using 4% polyacrylamide gel electrophoresis (PAGE) for the detection of BCR-ABL transcripts in Philadelphia-positive disease. Three out of 50 cases [two out of 37 chronic myeloid leukaemia (CML), one out of 13 acute lymphoblastic leukaemia (ALL)] possessed rare breakpoints; an e19a2 and e13a3 in CML and an e1a3 in the ALL. We suggest that multiplex...

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Share to Chromosome Breakage
Share to Electrophoresis, Polyacrylamide Gel

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fusion Proteins, bcr-abl

Share to Genotype

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to Philadelphia Chromosome

Share to Polymerase Chain Reaction

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Source

Identifiers

PMID: 11167748
DOI: 10.1046/j.1365-2141.2000.02471.x

Genes

BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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