Article
Localization of the Drosophila MAGUK protein Polychaetoid is controlled by alternative splicing.
Mechanisms of development - 1 Feb 2001
Wei X, Ellis H M
Abstract excerpt
The Drosophila membrane-associated guanylate kinase (MAGUK) protein Polychaetoid (Pyd) is required for dorsal closure of the embryo, sensory organ patterning, and cell fate specification in the developing eye. We demonstrate that pyd is alternatively spliced resulting in two isoforms that differ by the presence or absence of exon 6. To determine the role of alternative splicing in Pyd function, we generated...
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