Article
The C-terminus of human glutaminase L mediates association with PDZ domain-containing proteins.
FEBS letters - 19 Jan 2001
Olalla L, Aledo J C, Bannenberg G, Márquez J
Abstract excerpt
The enzyme glutaminase in brain is responsible for the synthesis of neurotransmitter glutamate. We used the two-hybrid genetic selection system in yeast to look for interactors of glutaminase in human brain. We have identified two proteins containing PDZ domains, alpha1-syntrophin and a glutaminase-interacting protein, named GIP, that showed association with human glutaminase L, as deduced from specificity test...
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