Article
RT-PCR diagnosis of recurrent rearrangements in pediatric acute lymphoblastic leukemia in Argentina.
Leukemia research - 1 Jun 2012
Alonso Cristina N, Gallego Marta S, Rossi Jorge G, Medina Adriana, Rubio Patricia L, Bernasconi Andrea R, Zubizarreta Pedro A, Felice María S
Abstract excerpt
The present study was performed to establish the prevalence of the recurrent fusion transcripts in Argentinean pediatric patients with acute lymphoblastic leukemia (ALL). A total of 380 newly diagnosed children (including 50 infants and 44 T-ALL) were screened by RT-PCR; the incidence of recurrent rearrangements was: ETV6-RUNX1, 12.9%; TCF3-PBX1, 5.0%; BCR-ABL1, 1.6%; and MLL rearrangements, 10.5%. STIL-TAL1 was...
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