Article
Biosynthetic basis of incompatible histo-blood group A antigen expression: anti-A transferase antibodies reactive with gastric cancer tissue of type O individuals.
Cancer research - 15 Nov 1993
David L, Leitao D, Sobrinho-Simoes M, Bennett E P, White T, Mandel U, Dabelsteen E, Clausen H
Abstract excerpt
The expression of incompatible A carbohydrate antigens in some adenocarcinomas may provide an explanation for the generally observed lower incidence of adenocarcinoma among types O and B versus type A individuals. The chemistry and genetic basis of incompatible A expression is largely unknown. Here, we have screened 31 cases of gastric tumors of phenotype O for the expression of blood group A gene-defined...
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