Article
Investigation into A antigen expression on O2 heterozygous group O-labeled red blood cell units.
Transfusion - 1 Aug 2008
Yazer Mark H, Hult Annika K, Hellberg Asa, Hosseini-Maaf Bahram, Palcic Monica M, Olsson Martin L
Abstract excerpt
BACKGROUND: There are two principal types of group O alleles; deletional alleles feature 261delG leading to nonfunctional truncated protein. Nondeletional alleles have the consensus guanosine at residue 261. The major nondeletional allele, O2, encodes full-length protein with Gly268Arg. While reports vary, O2 has been proposed to encode weakly functional A-glycosyltransferase (GTA). The main objective of this...
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