Article
Xylitol-induced elevated expression of the gbpC gene in a population of Streptococcus mutans cells.
European journal of oral sciences - 1 Dec 2000
Sato Y, Yamamoto Y, Kizaki H
Abstract excerpt
Xylitol possesses a unique property distinct from the other caries-preventive sweeteners. This sugar alcohol cannot be metabolized to acids but is taken up by Streptococcus mutans and accumulated as a toxic sugar-phosphate in the cells, resulting in growth inhibition. Due to the accumulation, xylitol induces biological responses including the emergence of xylitol-insensitive populations. Therefore, we expected...
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