Article
Fcgamma receptor polymorphisms in systemic lupus erythematosus: association with disease and in vivo clearance of immune complexes.
Arthritis and rheumatism - 1 Dec 2000
Dijstelbloem H M, Bijl M, Fijnheer R, Scheepers R H, Oost W W, Jansen M D, Sluiter W J, Limburg P C, Derksen R H, van de Winkel J G, Kallenberg C G
Abstract excerpt
OBJECTIVE: Fc receptors for IgG (FcgammaR) play a prominent role in the clearance of immune complexes in systemic lupus erythematosus (SLE). Polymorphisms of FcgammaR have been proposed as genetic factors that influence susceptibility to SLE. We analyzed 3 functional FcgammaR polymorphisms in a strictly Caucasian population of SLE patients, and determined the influence of these polymorphisms on the clearance of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
