Article
Automated, PCR-RFLP genotyping of the urokinase gene.
Genetic testing - 1 Jan 2000
Sell S M, Blasi F, Booyse F
Abstract excerpt
The urokinase-type plasminogen activator (u-PA) has been suggested to play a role in the early initiation and progression of atherosclerosis and coronary artery disease (CAD) (Grenett et aL, 1998). Recently, a common genetic polymorphism in the untranslated region of the u-PA gene was shown to be associated with syptomatic CAD. To study the possible role of this common genetic polymorphism in the u-PA gene, we...
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