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Article

Biochemical characterization of a neuroserpin variant associated with hereditary dementia.

The American journal of pathology - 1 Jan 2001

Yazaki M, Liepnieks J J, Murrell J R, Takao M, Guenther B, Piccardo P, Farlow M R, Ghetti B, Benson M D

Abstract excerpt

Neuroserpin isolated from inclusion bodies in the brain of a patient with a neurodegenerative disease was characterized biochemically. The protein consisted of residues 20 to 410 of the neuroserpin precursor deduced from its cDNA sequence indicating the entire molecule was deposited. A minor amount started with residue 19 of the precursor, and the carboxyl terminus was heterogeneous ending at residues 405, 407,...

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Share to Brain
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Share to Electrophoresis, Polyacrylamide Gel

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neuropeptides

Share to Polymorphism, Restriction Fragment Length

Share to Sequence Analysis, Protein

Share to Sequence Homology, Amino Acid

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Source

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Identifiers

PMID: 11141496
DOI: 10.1016/S0002-9440(10)63961-2
PMCID: PMC1850267

Genes

AGT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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