Article
Viable rabbits derived from reconstructed Oocytes by germinal vesicle transfer after intracytoplasmic sperm injection (ICSI)
1 Jan 2000
Abstract excerpt
Abnormal oocyte spindle due to the improper function of ooplasm is associated with female infertility of advanced maternal age. A possible way to overcome this problem is to transfer an oocyte germinal vesicle (GV) which contains genetic materials of a patient with a history of poor embryo development to the cytoplast from a donor oocyte. Here we demonstrate that GV transfer is feasible using a rabbit model. When...
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