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Article

Positive or negative MARE-dependent transcriptional regulation is determined by the abundance of small Maf proteins.

Cell - 8 Dec 2000

Motohashi H, Katsuoka F, Shavit J A, Engel J D, Yamamoto M

Abstract excerpt

The small Maf transcription factor proteins bind to Maf Recognition Elements (MAREs) by dimerizing with CNC proteins or themselves. We undertook experiments to clarify the functional relationship between the small Mafs and their partners in vivo. Embryos expressing abundant transgene-derived MafK died of severe anemia, while lines expressing lower levels of small Maf lived to adulthood. Megakaryocytes from the...

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PMID: 11136972
DOI: 10.1016/s0092-8674(00)00190-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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