Article
Impaired megakaryopoiesis and behavioral defects in mafG-null mutant mice.
Genes & development - 15 Jul 1998
Shavit J A, Motohashi H, Onodera K, Akasaka J, Yamamoto M, Engel J D
Abstract excerpt
The small Maf proteins (MafG, MafK, and MafF), which serve as heterodimeric partner molecules of CNC family proteins for binding in vitro to MARE sites, have been implicated in the regulation of both transcription and chromatin structure, but there is no current evidence that the proteins fulfill...
Topics
- Animals
- Blood Platelets
- DNA-Binding Proteins
- Embryonic and Fetal Development
- Female
- Fertility
- Gene Targeting
- Hematopoiesis
- MafG Transcription Factor
- MafK Transcription Factor
- Male
- Megakaryocytes
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Nuclear Proteins
- Phenotype
- Repressor Proteins