Article
Neuroblastoma cell lines showing smooth muscle cell phenotypes.
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Dec 2000
Sugimoto T, Mine H, Horii Y, Takahashi K, Nagai R, Morishita R, Komada M, Asada Y, Sawada T
Abstract excerpt
Neuroblastoma is a tumor that is derived from the neural crest. Recent studies demonstrated that several human neuroblastoma cell lines exhibit at least three morphologic types: neuroblastic (N)-type, substrate-adhesive (S)-type and intermediate (I)-type cells. However, the origin of the S-type cells has not been clearly identified. In this study, the expressions of smooth muscle-specific proteins (desmin,...
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