Article
Anaplastic changes associated with p53 gene mutation in differentiated thyroid carcinoma after insufficient radioactive iodine (131I) therapy.
Thyroid : official journal of the American Thyroid Association - 1 Nov 2000
Sera N, Ashizawa K, Ando T, Ide A, Abe Y, Usa T, Tominaga T, Ejima E, Hayashi T, Shimokawa I, Eguchi K
Abstract excerpt
Thirty-two patients with differentiated thyroid carcinomas with distant metastasis were examined using a radioactive iodine (131I) tracer dose prior to 131I therapy and followed up for 10 years or until death (whichever occurred first). Nineteen patients who received 131I therapy had an accumulation of 131I in the metastases (group I) and 15 of those patients were alive more than 10 years after the first 131I...
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