Article
Decreased expression of Fas (APO‐1/CD95) on peripheral blood CD4+ T lymphocytes in cutaneous T‐cell lymphomas
1 Dec 2000
Abstract excerpt
BACKGROUND: The usually protracted and indolent course of cutaneous T-cell lymphoma (CTCL) is consistent with an accumulation of lymphocytes rather than being a true proliferative disorder, perhaps as the result of defective lymphocyte apoptosis. Fas (CD95) is the main signalling membrane molecule involved in postactivation T-lymphocyte apoptosis. OBJECTIVES: To evaluate expression of Fas on circulating CD4+...
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