Article
Reversible resistance to apoptosis in cutaneous T cell lymphoma.
Annals of the New York Academy of Sciences - 1 Sept 2001
Meech S J, Edelson R, Walsh P, Norris D A, Duke R C
Abstract excerpt
Mycosis fungoides and its leukemic variant, Sézary syndrome, represent the most common forms of cutaneous T cell lymphomas (CTCL). These disorders are clonal neoplasms characterized by the progressive accumulation of cells that resemble activated/memory CD4+ T cells. Unlike their normal counterparts, these malignant lymphocytes have prolonged life spans and are resistant to dying following treatment with most...
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