Chromaffin-adrenocortical cell interactions: effects of chromaffin cell activation in adrenal cell cocultures.

Abstract excerpt

Although the adrenal cortex and medulla are both involved in the maintenance of homeostasis and stress response, the functional importance of intra-adrenal interactions remains unclear. When primary cocultures of frog (Rana pipiens) adrenocortical and chromaffin cells were used, selective chromaffin cell activation dramatically affected both chromaffin and adrenocortical cells. Depolarization with 50 microm...

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