Article
Allelic deletions of cell growth regulators during progression of bladder cancer.
Cancer research - 1 Dec 2000
Primdahl H, von der Maase H, Christensen M, Wolf H, Orntoft T F
Abstract excerpt
Cell growth regulators include proteins of the p53 pathway encoded by the genes CDKN2A (p16, p14arf), MDM2, TP53, and CDKN1A (p21) as well as proteins encoded by genes like RB1, E2F, and MYCL. In the present study we investigated allelic deletions of all these genes in each recurrent bladder tumor from well-defined clinical material with more than 3 years of follow-up. We followed three groups (22 or 23...
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