Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human complex I defects can be resolved by monoclonal antibody analysis into distinct subunit assembly patterns.

The Journal of biological chemistry - 23 Mar 2001

Triepels R H, Hanson B J, van den Heuvel L P, Sundell L, Marusich M F, Smeitink J A, Capaldi R A

Abstract excerpt

Complex I defects are one of the most frequent causes of mitochondrial respiratory chain disorders. Therefore, it is important to find new approaches for detecting and characterizing Complex I deficiencies. In this paper, we introduce a new set of monoclonal antibodies that react with 39-, 30-, 2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cattle
Share to Cells, Cultured

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primers

Share to Electron Transport Complex I

Share to Mutation

Share to NADH, NADPH Oxidoreductases

Source

Identifiers

PMID: 11112787
DOI: 10.1074/jbc.M009903200

Genes

NDUFS2
NDUFS4
NDUFS7
NDUFS8
NDUFV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11112787-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human complex I defects can be resolved by monoclonal antibody analysis into distinct subunit assembly patterns.PMID 11112787Read ↗

Investigation of the complex I assembly chaperones B17.2L and NDUFAF1 in a cohort of CI deficient patients.Semantic proximity Read ↗

Using a quantitative quadruple immunofluorescent assay to diagnose isolated mitochondrial Complex I deficiency.Semantic proximity Read ↗

Immunological phenotyping of fibroblast cultures from patients with a mitochondrial respiratory chain deficit.Semantic proximity Read ↗

Differences in assembly or stability of complex I and other mitochondrial OXPHOS complexes in inherited complex I deficiency.Semantic proximity Read ↗

Human CIA30 is involved in the early assembly of mitochondrial complex I and mutations in its gene cause disease.Semantic proximity Read ↗

Congenital deficiency of a 20-kDa subunit of mitochondrial complex I in fibroblasts.Semantic proximity Read ↗

An immunocytochemical approach to detection of mitochondrial disorders.Semantic proximity Read ↗

A Mutation in the Flavin Adenine Dinucleotide-Dependent Oxidoreductase FOXRED1 Results in Cell-Type-Specific Assembly Defects in Oxidative Phosphorylation Complexes I and II.Semantic proximity Read ↗

Human mitochondrial complex I assembly is mediated by NDUFAF1.Semantic proximity Read ↗

The arginine methyltransferase NDUFAF7 is essential for complex I assembly and early vertebrate embryogenesis.Semantic proximity Read ↗

Analysis of the mitochondrial encoded subunits of complex I in 20 patients with a complex I deficiency.Semantic proximity Read ↗

Analysis of compound heterozygous and homozygous mutations found in peripheral subunits of human respiratory Complex I, NDUFS1, NDUFS2, NDUFS8 and NDUFV1, by modeling in the E. coli enzyme.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.