Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

True epithelial hyperplasia in the thymus of early-onset myasthenia gravis patients: implications for immunopathogenesis.

Journal of neuroimmunology - 1 Jan 2001

Roxanis I, Micklem K, Willcox N

Abstract excerpt

The early-onset myasthenia gravis (EOMG) thymus shows characteristic medullary epithelial bands (MEB), greatly expanded perivascular infiltrates and fenestrations of the intervening basement membranes. We now compare epithelial expression of epidermal growth factor receptor (EGFR) and many integrins in EOMG and control samples. The main differences are striking/consistent thickening (in MEB) of what is normally a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Movement
Share to Epithelial Cells
Share to ErbB Receptors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Extracellular Matrix Proteins

Share to Hyperplasia

Share to Integrins

Share to Myasthenia Gravis

Share to Thymus Gland

Source

Identifiers

PMID: 11108945
DOI: 10.1016/s0165-5728(00)00415-x

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

True epithelial hyperplasia in the thymus of early-onset myasthenia gravis patients: implications for immunopathogenesis.PMID 11108945Read ↗

Clonal heterogeneity of thymic B cells from early-onset myasthenia gravis patients with antibodies against the acetylcholine receptor.Semantic proximity Read ↗

Myasthenia gravis-specific aberrant neuromuscular gene expression by medullary thymic epithelial cells in thymomaSemantic proximity Read ↗

Myasthenia gravis-specific aberrant neuromuscular gene expression by medullary thymic epithelial cells in thymomaSemantic proximity Read ↗

Ectopic GC in the thymus of myasthenia gravis patients show characteristics of normal GCSemantic proximity Read ↗

Late-onset myasthenia gravis - CTLA4(low) genotype association and low-for-age thymic output of naïve T cells.Semantic proximity Read ↗

Pathomechanisms of paraneoplastic myasthenia gravis.Semantic proximity Read ↗

Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravisSemantic proximity Read ↗

Role of miRNAs in Normal and Myasthenia Gravis ThymusSemantic proximity Read ↗

GKLF in thymus epithelium as a developmentally regulated element of thymocyte-stroma cross-talkSemantic proximity Read ↗

A pathogenetic role for the thymoma in myasthenia gravis. Autosensitization of IL-4- producing T cell clones recognizing extracellular acetylcholine receptor epitopes presented by minority class II isotypes.Semantic proximity Read ↗

HHV-6B, HHV-7, and B19V Are Frequently Found DNA Viruses in the Human Thymus but Show No Definitive Link with Myasthenia GravisSemantic proximity Read ↗

Scenarios for autoimmunization of T and B cells in myasthenia gravis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.