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Article

Loss of Fas-ligand expression in mouse keratinocytes during UV carcinogenesis.

The American journal of pathology - 1 Dec 2000

Ouhtit A, Gorny A, Muller H K, Hill L L, Owen-Schaub L, Ananthaswamy H N

Abstract excerpt

Skin cells containing excessive ultraviolet (UV) radiation-induced DNA damage are eliminated by apoptosis that involves the p53 pathway and Fas/Fas-Ligand (Fas-L) interactions. To determine whether dysregulation of apoptosis plays a role in skin cancer development through disruption of Fas/Fas-L interactions, hairless SKH-hr1 mice were exposed to chronic UV irradiation from Kodacel-filtered FS40 lamps for 30...

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Share to Fas Ligand Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11106570
DOI: 10.1016/S0002-9440(10)64836-5
PMCID: PMC1885778

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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