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Article

Functional and Ultrastructural Features of DNA‐Fragmented Human Sperm

12 Nov 2000

Abstract excerpt

The functional significance of deoxyribonucleic acid (DNA) fragmentation in ejaculated human sperm is unclear. In this study the extent of DNA strand breakage in swim-up selected spermatozoa was evaluated by terminal deoxynucleotidyl transferase-mediated fluorescein-dUTP nick end labeling (TUNEL)-coupled flow cytometry and correlated with several functional and morphological sperm parameters. The extent of DNA...

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PMID: 11105917
DOI: 10.1002/j.1939-4640.2000.tb03421.x

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