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Progressive genetic aberrations detected by comparative genomic hybridization in squamous cell cervical cancer

1 Dec 2000

Abstract excerpt

Genetic changes orchestrated by human papillomaviruses are the most important known factors in carcinogenesis of the uterine cervix. However, it is clear that additional genetic events are necessary for tumour progression. We have used comparative genomic hybridization to document non-random chromosomal gains and losses within a subset of 37 cervical carcinomas matched for clinical stage Ib, but with different...

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PMID: 11104563
DOI: 10.1054/bjoc.2000.1509

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